Endozepine stupor. Recurring stupor linked to endozepine-4 accumulation
نویسندگان
چکیده
منابع مشابه
Endozepine stupor. Recurring stupor linked to endozepine-4 accumulation.
Recurring stupor can be caused by repeated metabolic, toxic or structural brain disturbances. Recently, cases of recurring stupor, with fast EEG activity were shown to display increased endogenous benzodiazepine-like activity during the episodes of stupor. Patients with recurring stupor underwent extensive metabolic and toxicologic screening, EEG and brain imaging. Endozepines and exogenously a...
متن کاملModafinil in endozepine stupor. A case report.
BACKGROUND Endozepine-4 stupor is a rare disorder. It presents with recurrent episodes of stupor and coma. Endozepine-4 levels are elevated during an attack with electroencephalogram showing fast activity during the ictal phase. There is no specific treatment and various drugs have been tried without long-term benefit. METHOD We used the vigilance promoting drug modafinil to prevent such atta...
متن کاملSuspected covert lorazepam administration misdiagnosed as recurrent endozepine stupor.
We recently reported in Brain (Lugaresi et al., 1998) 20 cases of idiopathic recurrent stupor due to endozepine-4 accumulation in the blood. Samples obtained from nine of these patients were analysed by gas chromatography–mass spectrometry to rule out contaminating synthetic benzodiazepines (Rothstein et al., 1992). All these samples contained endozepine-4 concentrations high enough to account ...
متن کاملManic Stupor
Mr. AR, a 24-year-old carpenter, was. brought into treatment for first-episode psychiatric illness. According to reports, AR's alteredbehaviour began suddenly, 2 days earlier and comprised hostility towards all and sundry, prolonged spells of shouting and abusiveness, mindless violence, almost total absence of sleep, and refusal of food. There was no past, personal, or family history of signifi...
متن کاملTreating Manic Stupor
The unusual feature of this case was the development of manic stupor. Although this condition is described in classical texts (e.g. Hamilton. 1974). in clinical practice most psychiatrists never see a case in their lifetime. It is seldom easy to make the diagnosis prospectively Usually, several differential diagnoses are entertained, including neuroleptic malignant syndrome, for such patients h...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Brain
سال: 1998
ISSN: 1460-2156
DOI: 10.1093/brain/121.1.127